Crossover junction endonuclease mus81

Author: jcfb

August undefined, 2024

WebMUS81 Antibodies. Antibodies that detect MUS81 can be used in several scientific applications, including Western Blot, Immunocytochemistry and Immunohistochemistry. These antibodies target MUS81 in Human, Rat and Mouse samples. Our MUS81 polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. WebAbx , Every proteiIdentifier , Protein names , Gene names , Cross reference refseq , Length

Gene structures of plant MUS81 genes. (A) Schematic …

WebFeb 7, 2011 · Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the … WebProduct Specs; Item Recombinant Neurospora crassa Crossover junction endonuclease mus-81 (mus-81), partial; Company MyBioSource.com; Price Supplier Page View Company Product Page; Catalog Number MBS1286867; Purity >90%; Type Recombinant Protein; Molecule Name Crossover junction endonuclease mus-81 (mus-81), partial; Format … paraffate

Mus81 - PCR Primer Pair - SYBR PrimePCR Bio-Rad

WebAbstract Hef is an archaeal member of the DNA repair endonuclease XPF (XPF)/Crossover junction endonuclease MUS81 (MUS81)/Fanconi anemia, complementation group M (FANCM) protein family that in eukaryotes participates in the restart of stalled DNA replication forks. WebMar 1, 2024 · crossover junction endonuclease MUS81 [EC:3.1.22.-] Organism: dre Danio rerio (zebrafish) Pathway: dre03440 : Homologous recombination: dre03460 : Fanconi anemia pathway ... 406839 (mus81) 03460 Fanconi anemia pathway 406839 (mus81) 09180 Brite Hierarchies 09182 Protein families: genetic information processing 03400 … WebMar 29, 2024 · EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008] ... probable crossover junction endonuclease EME2, SLX2 structure-specific endonuclease subunit homolog B, essential meiotic … parafernalia revolution

Roles of SLX1–SLX4, MUS81–EME1, and GEN1 in avoiding …

WebNov 19, 2024 · Data indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4. FBH1 helicase … WebThis gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination … parafernalia revolution ballpoint penWebGene mus81 ID ZDB-GENE-040426-2923 Name MUS81 structure-specific endonuclease subunit Symbol mus81 Nomenclature History Previous Names wu:fc26g01 zgc:66489 zgc:91801 Type protein_coding_gene Location Chr: 7 Mapping Details/Browsers Description Predicted to enable 3'-flap endonuclease activity. おしゃれ無料イラスト

"WebPTHR13451 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 2 hits; Pfam. View protein in Pfam; PF02732 ERCC4 1 hit; SMART. View protein in SMART; SM00891 ERCC4 1 hit; SUPFAM. SSF47802 DNA polymerase beta, N-terminal domain-like 1 hit; SSF52980 Restriction endonuclease-like 1 hit; MobiDB. " - Crossover junction endonuclease mus81

Crossover junction endonuclease mus81

http://www.ab-mart.com/proteinantibodies/List?page=80 WebCrossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. [5] [6] It forms a complex with MUS81 which resolves Holliday junctions. In mammalian cells the EME1/ MUS81 protein complex is redundant for DNA damage repair with GEN1 endonuclease. [7]

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WebMar 21, 2024 · Mus81 is a novel prognostic marker for colorectal carcinoma; Mus81 down-regulation correlated significantly to invasion depth (p = 0.015) and poorly-differentiated … WebThis constitutes an important mechanism of crossover avoidance, which otherwise can lead to loss of heterozygosity and cancer predisposition. ... The structure-specific endonuclease MUS81 contributes to replication restart by generating double-strand DNA breaks. ... Coordinated actions of SLX1–SLX4 and MUS81–EME1 for Holliday junction ...

Webcrossover junction DNA endonuclease activity: GO Molecular Function enables 3'-flap endonuclease activity, endonuclease activity: Growth and Developmental Stages ... Fewer bivalents then the msh4 mus81-2 double mutant; 67.6% of the msh4 mus81-2 fancd2-1 triple mutant meiocytes contain no bivalents (2.4% in the double mutant); 26.5% of the … WebXPF-like nuclease domain of Mus81. Mus81 is a crossover junction endonuclease that interacts with Eme1 and Eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. The typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions.

Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. In mammalian somatic cells, MUS81 and another structure specific DNA endonuclease, XPF (ERCC4), play overlapping and essential roles in completion of homologous recombination. The significant overlap … See more MUS81 is a component of a minor chromosomal crossover (CO) pathway in the meiosis of budding yeast, plants and vertebrates. However, in the protozoan Tetrahymena thermophila, MUS81 appears to be part of an … See more MUS81 has been shown to interact with CHEK2. See more • Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. • Suzuki Y, Yoshitomo … See more WebJan 5, 2024 · This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures.

WebFeb 1, 2024 · The catalytic subunits of XPF and MUS81 display a GDXnERKX3D active site motif that is required for metal-dependent endonuclease activity but not DNA junction binding (Enzlin and Schärer 2002; Nishino et al. 2003). In contrast, Zip2, ... Sgs1 and Mus81/Mms4 in crossover formation. PLoS Genet 10: e1004870. [PMC free article] ...

WebFeb 22, 2014 · The Mus81-Eme1 complex is a structure-selective endonuclease with a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, or double-strand breaks. おしゃれ無料フォントWebCrossover junction endonuclease Mus81 protein was identified by screening a human cerebellum cDNA library with a probe from the yeast Mus81. The human Mus81 has 551 amino acids with a molecular mass of 59 kDa. The highest sequence similarity between different species is around the VERKX3D motif. オシャレ煙WebFeb 15, 2024 · crossover junction endodeoxyribonuclease ( 3.1.21.10 ) Gene Summary mus81 ( mus81) encodes the catalytic subunit of the Mus81-mms4 structure-selective endonuclease that functions in DNA repair. [Date last reviewed: 2024-03-14] ( FlyBase Gene Snapshot ) All Summaries Gene Snapshot Gene Group Also Known As … おしゃれ無料背景