Fun14 domain-containing protein 2

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August undefined, 2024

WebMar 9, 2024 · FUN14 domain-containing protein 2, HCC-3, cervical cancer oncogene 3, cervical cancer proto-oncogene 3 protein, hepatitis C virus core-binding protein 6. … WebWe observed that FUN14 domain-containing 1 (FUNDC1), a previously characterized mitophagy receptor, accumulates in most human hepatocellular carcinomas (HCCs), and …

FUNDC2 - DECIPHER v11.18

WebMar 1, 2003 · FUN14 domain-containing protein 1. Gene names. Name. FUNDC1. Organism names. Organism. Homo sapiens (Human) Taxonomic identifier. 9606 NCBI. … WebFUNDC2. Forward strand gene: FUN14 domain containing 2. Also known as: DC44, HCBP6, ENSG00000165775. Function: Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho- (1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT ... thoiry chateau

FUN14 Domain‐Containing 1–Mediated Mitophagy Suppresses …

WebFUN14 DOMAIN-CONTAINING PROTEIN 1; FUNDC1 HGNC Approved Gene Symbol: FUNDC1. Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:44,523,639-44,542,859 (from NCBI) TEXT Description. FUNDC1 is an integral mitochondrial outer membrane protein that mediates hypoxia-induced ... WebRecently, FUN14 domain-containing protein 1 (FUNDC1) has been identiﬁed as a new outer mitochondrial membrane protein localized in MAMs [20,21]. FUNDC1 regulates the MAM formation responsible for Ca2+ release from the ER into mitochondria and cytosol in mouse cardiomyocytes. Moreover, overexpression of FUNDC1 was sufﬁcient WebNov 25, 2016 · The results of the current study revealed an interaction between the TPR domain of KLC1 and FUN14 domain‑containing protein 1 (FUNDC1), which is a mitochondrial outer membrane protein mediating hypoxia‑induced mitophagy. FUNDC1 bound to the six TPR motif-containing regions of KLC1 and did not interact with KIF5B … thoiry illuminations 2022

FUN14 domain-containing 1 promotes breast cancer …

Fundc2 MGI Mouse Gene Detail - MGI:1914641 - FUN14 domain containing 2

WebNov 1, 2024 · In this study, we investigated FUN14 domain containing 1 (FUNDC1)-mediated mitophagy in the regulation of interleukin-1β (IL-1β) in vitro and in vivo, ... Bcl-2/E1B 19 kDa-interacting protein 3 (BNIP3), Bcl-2/E1B 19 kDa-interacting protein 3-like protein (BNIP3L/NIX) and FUNDC1. FUNDC1 is a mitochondrial outer membrane … WebJul 1, 2024 · BCL2-interacting protein 3 (BNIP3), BCL2-interacting protein like (BNIP3L/NIX), FUN14 domain-containing 1 (FUNDC1), optineurin (OPTN), calcium-binding and coiled-coil domain 2 (CALCOCO2/NDP52), and cardiolipin (CL) (purple boxes) also identify mitochondria to be degraded. thoiry 78 commercesWebNov 22, 2024 · PINK1–Parkin independent mitophagy employs several receptors: BNIP3 (Bcl-2/adenovirus E1B protein interacting with protein 3), Nix/BNIP3L (Nip3-like protein X), FUNDC1 (FUN14 domain-containing protein 1), and cardiolipin. They are localized in mitochondria and interact with LC3, attracting autophagosomes to damaged mitochondria. thoiry immobilier avis

"WebFundc2 knockout mice developed an excess of apoptotic platelets and thrombocytopenia in response to hypoxia. Ma et al. (2024) showed that the N terminus of the FUNDC2 … " - Fun14 domain-containing protein 2

Fun14 domain-containing protein 2

65991 - Gene ResultFUNDC2 FUN14 domain containing 2 …

WebThe results of the current study revealed an interaction between the TPR domain of KLC1 and FUN14 domain-containing protein 1 (FUNDC1), which is a mitochondrial outer membrane protein mediating hypoxia-induced mitophagy. FUNDC1 bound to the six TPR motif-containing regions of KLC1 and did not interact with KIF5B (a motor subunit of … http://m.labbase.net/IndustryNewsDetial-140597.html

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WebBNIP3L, a single pass OMM protein, requires its transmembrane domain (TM) for proper OMM localization [Citation 24]. Moreover, studies have shown that BNIP3L is a 24-kDa protein, which is predominantly expressed as a 48-kDa dimer, suggesting that BNIP3L dimerization might have a functional role [Citation 5, Citation 25]. As the molecular ... WebFUNDC2, FUN14 domain containing 2. Synonyms DC44, HCBP6, HCC3, PD03104 Links HGNC:24925. NCBI Gene ID: 65991. neXtProt AC ... protein-containing complex. …

WebThere is a very high volume of traffic coming from your site (IP address 40.79.131.210) as of Mon Apr 10 11:46:10 2024 (California time). So that other users get a fair share of our bandwidth, we are putting in a delay of 10.3 seconds before we service your request. WebMay 13, 2024 · Dysfunction in mitophagy is involved in the molecular mechanism responsible for the onset and development of human diseases. FUN14 domain …

WebFeb 7, 2011 · Bcl-2-like protein 13: K08860 : eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] K04374 : cyclic AMP-dependent transcription factor ATF-4: ... FUN14 domain-containing protein 1: K08268 : hypoxia-inducible factor 1 alpha: K17454 : transcription factor E2F1: K04735 : transcription factor p65:

http://www.informatics.jax.org/marker/MGI:1914641

WebDec 1, 2024 · Another mitophagy receptor activated by hypoxia is FUNDC1 (FUN14 domain-containing protein 1) [39, 40]. In response to hypoxia, FUNDC1 binds to MAP1LC3B via its LIR motif and facilitates mitophagy through autophagosome formation . Phosphorylation of FUNDC1 at a tyrosine residue in the LIR motif by SCR1 kinase … thoiry lodgeWebDec 5, 2024 · Background:FUN14 domain containing 1 (FUNDC1) is a highly conserved outer mitochondrial membrane protein. The aim of this study is to examine whether FUNDC1 modulates the mitochondria … thoiry immobilier thoiryWebPredicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC2 (FUN14 domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine. Type: protein-coding RefSeq Status: VALIDATED: Previously known as: FUN14 domain-containing protein 2; LOC361288; RGD1560916; similar to … thoiry hotelsWebFUNDC2, FUN14 domain containing 2. Synonyms DC44, HCBP6, HCC3, PD03104 Links HGNC:24925. NCBI Gene ID: 65991. neXtProt AC ... protein-containing complex. synapse. vacuole. Click cells to view annotations. Expression less. Expression Overview early conceptus ... thoiry scolaireWebWe observed that FUN14 domain-containing 1 (FUNDC1), a previously characterized mitophagy receptor, accumulates in most human hepatocellular carcinomas (HCCs), and we thus explored the role of FUNDC1-mediated mitophagy in HCC initiation and progression in a mouse model in which HCC is induced by the chemical carcinogen, diethylnitrosamine … thoiry mairieWebSep 1, 2024 · FUN14 domain-containing 1 (FUNDC1) is a newly identified mitochondrial outer membrane protein that induces receptor-mediated mitophagy by its interaction … thoiry france hotelsWebJul 14, 2024 · Molecular pathways such as the signal pathways with the involvement of PTEN-induced putative kinase protein 1 (PINK1)/Parkin, BCL2/adenovirus E1B 19kDa-interacting protein 3/Nip3-like protein X (Bnip3/Nix), and FUN14 domain containing 1 (FUNDC1) are mainly responsible for regulating mitophagy. thoiry location