WebNational Center for Biotechnology Information WebFinally, the expression of GBP4, the identified hub gene, strongly correlated with the infiltration of M1 macrophages (adjusted r-squared =0.661, p < 2×10 ⁻¹⁶ ), and is a relatively good ...
Immune cell - GBP4 - The Human Protein Atlas
WebBy IFNG during macrophage activation. GBP4 protein sequence . This sequence information is just for reference only. From Uniport. Length. 640.00. Mass (KDa) 73.00. Learn more about GBP4 protein information & reagent. GBP4 Gene . GBP4 cDNA / gene is a gene with protein product which located on 1p22.2. The GBP4 gene is conserved in … WebSep 16, 2024 · Similarly, GBP5 is the key activator protein of AIM2 which activates caspase-1 in mouse macrophages through ASC in response to Francisella infection (Meunier et al., 2015). ... GBP4 expression is 3.039644 ± 0.9899737 in PD group, 3.232032 ± 1.0081706 in SD group, 3.205698 ± 1.0478816 in PR group and 3.886223 ± 1.1831482 in CR group. ... fruitland early childhood
Epromoters function as a hub to recruit key transcription ... - Nature
WebNational Center for Biotechnology Information WebFeb 18, 2024 · GBP1 is highly expressed in macrophages, endothelial cells, and epithelial cells and is induced by interferon-gamma (IFN-у). ... GBP3, and GBP4. Caspase-4 is then drawn to the LPS and GBP complex forming the caspase-4 activation platform. Activated caspase then cleaves Gasdermin D resulting in the release of the N-terminal effector … WebNov 18, 2024 · To induce macrophage differentiation, THP-1 cells were firstly plated on 6-well plates (2 × 10 6 cells/well), in media containing 10 ng/mL phorbol 12-myristate 13-acetate (PMA; Sigma-Aldrich ... gidget wichita falls