WebRaes G, Ghassabeh GH, Brys L, Mpofu N, Verschueren H, Vanhecke D, De Baetselier P. Laboratory of Cellular and Molecular Immunology, Department of Molecular ... that the … WebSelectins are a family of transmembrane proteins containing an amino-terminal lectin domain for binding to ligands, an epidermal growth factor (EGF)-like domain, 2–9 regulatory protein repeats, a transmembrane domain, and a short cytoplasmic tail.

Frontiers P-Selectin Glycoprotein Ligand 1: A Potential HIV-1

WebJun 21, 2009 · Laszik, Z. et al. P-selectin glycoprotein ligand-1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. Blood 88, … WebAug 28, 2001 · P-selectin is a member of the selectin family of adhesion molecules. PSGL-1 on the plasma membranes of neutrophils or monocytes, which are key effector cells of the innate immune system, binds to P-selectin translocated to the surfaces of inflamed endothelial cells or activated platelets (Fig. 1 ). napa auto parts williams ca

P Selectin Glycoprotein Ligand 1 - an overview

WebBackground P-selectin glycoprotein ligand-1 (PSGL-1/CD162) has been studied extensively for its role in mediating leukocyte rolling through interactions with its cognate receptor, P … WebDec 4, 2014 · The major ligand for P-selectin is P-selectin glycoprotein ligand-1 (PSGL-1, CD 162), constitutively expressed by leukocytes. It, together with CD44, can bind to E-selectin and L-selectin [ 6 ]. E-selectin and P-selectin are expressed on the cell-surface of endothelial cells by pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6 [ 7 ]. WebP-selectin glycoprotein ligand-1 (PSGL-1) is expressed on the surface of most leukocytes and is a counter-receptor for P-selectin. 122 It has been shown to bind E- and L-selectin, … meins alterations long beach ms