Phenytoin sodium ld50
WebJan 1, 2024 · Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer.Target: Sodium ChannelPhenytoin sodium is an antiepileptic drug. It is useful to … WebFeb 1, 2024 · Phenytoin Sodium Injection, USP is a sterile solution containing in each mL phenytoin sodium 50 mg, propylene glycol 0.4 mL and alcohol 0.1 mL in Water for Injection. pH 10.0-12.3; sodium hydroxide added, if needed, for pH adjustment. Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring.
Phenytoin sodium ld50
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WebThere is a smooth and rapid onset of unconsciousness. At the lethal dose, there is depression of vital medullary respiratory and vasomotor centers. When administered intravenously, phenytoin sodium produces toxic signs of cardiovascular collapse and/or central nervous system depression. Hypotension occurs when the drug is administered … Webphenytoin sodium infusion. A dose of 15 to 20 mg PE/kg of fosphenytoin sodium injection infused at 100 to 150 mg PE/min yields plasma free phenytoin concentrations over time …
WebThe recommended starting dose for adult patients who have received no previous treatment is one 100-mg DILANTIN (extended phenytoin sodium capsule, USP) by mouth three times daily. Adjust the dosage to suit individual requirements up to a maximum of two capsules three times a day. For most adults, the satisfactory maintenance dosage will be one ... WebNov 7, 2024 · Hair growth. Constipation. Increased blood sugar. Serious side effects of phenytoin are less common but may still occur. If you experience any of the following, or any other concerning side effects, seek medical attention immediately: Yellowing of the skin or eyes. Allergic reactions, such as rash, blisters, swelling of the mouth or face, tight ...
WebSep 19, 2024 · The pharmacological class of the fosphenytoin sodium is hydantoin derivative, and the therapeutic class is anticonvulsant. CEREBYX is marketed in 2 mL vials containing a total of 100 mg PE and 10 mL vials containing a total of 500 mg PE, for intravenous or intramuscular administration. The concentration of each vial is 50 mg … WebPhenytoin sodium - ≤ 100 Acute Tox. 4 (Orală), H302 (ATE=500 mg/kg greutate corporală) Carc. 2, H351 Repr. 1B, H360D Textul complet al frazelor H și EUH: a se vedea secțiunea 16 3.2. Amestecuri Neaplicabil SECȚIUNEA 4: Măsuri de …
WebParenteral Phenytoin Sodium Injection is indicated for the treatment of generalized tonic clonic status epilepticus and prevention and treatment of seizures occurring during …
WebSep 19, 2024 · DILANTIN (phenytoin sodium) injection, USP is a sterile solution of 50 mg phenytoin sodium per milliliter for intravenous or intramuscular administration. The solution is in a vehicle containing 40% propylene glycol and 10% alcohol in water for injection, adjusted to pH 12 with sodium hydroxide. lymphatic duct vs thoracic ductWebPhenytoin sodium. C15H11N2O2Na. Synonyms: 5,5-Diphenylhydantoin sodium salt, 5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin. CAS 630-93-3. Molecular Weight 274.25. Browse Phenytoin sodium and related products at MilliporeSigma. lymphatic earringsWebsodium injection that gives a rate and extent of phenytoin systemic availability similar to that of a 50 mg/min phenytoin sodium infusion. A dose of 15 to 20 mg PE/kg of fosphenytoin sodium injection infused at 100 to 150 mg PE/min yields plasma free lymphatic education and research network