Ttc9a

Author: ibgg

August undefined, 2024

WebRelative TTC9A mRNA increased by threefold in the uterus (J) on E2B treatment. 36B4 was used as the cDNA input control. Data analyzed by Mann-Whitney non-parametric … WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neurop …

Up-regulation of mammary TTC9A in involution is associated with …

WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the possible mechanisms of TTC9A on estradiol and neuroplasticity-related changes remain obscure. In this study, we investigated the effects of TTC9A and estradiol WebAnti-TTC9 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Synonyms: Anti … inconsistency\u0027s 3e

Tetratricopeptide repeat domain 9A is an interacting …

WebWe'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2024 ... WebAug 12, 2008 · TTC9A (1–100), which contains the first TPR domain, interacted with Tm5NM-1 to some extent but the interaction was weaker than TTC9A (1–115). Since the first TPR domain lies in residues 57–90, it is plausible that the first TPR domain is required for the interaction. WebTTC9A to be 222 aa. Using mouse polyclonal antibody generated against TTC9A protein, TTC9A was shown to be ubiquitously expressed in human tissues. In breast cancer cells, TTC9A was predominantly concentrated to the endoplasmic reticulum and was regulated by a number of factors, such as growth factors, serum factors and steroid hormones [2]. inconsistency\u0027s 36

TTC9A deficiency induces estradiol-mediated changes in

Web15 rows · Mar 21, 2024 · GeneCards Summary for TTC9 Gene. TTC9 (Tetratricopeptide Repeat Domain 9) is a Protein Coding gene. Diseases associated with TTC9 include Large … WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating aberration in hormone receptor signaling in absence of TTC9A.These observations suggest that TTC9A negatively regulates mammary gland development and the possibility that … inconsistency\u0027s 3dWebLi Quan, Wing Shan Yu, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Ying-Shing Chan, Valerie CL Lin and Lee Wei Lim (2024) TTC9A deficiency induces estradiol-mediated … inconsistency\u0027s 3g

"WebSep 14, 2012 · TTC9A was induced by mitogens, estrogen and growth factors in breast cancer cells MCF-7 [2]. TTC9A expression is also significantly higher in breast cancer tissues than the adjacent normal tissues [17]. These indicate that TTC9A expression is positively associated with cell proliferation and the presence of growth-stimulating signals. " - Ttc9a

Ttc9a

Tetratricopeptide repeat domain 9A modulates anxiety‑like …

WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system … WebTetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone. It is over-expressed in breast cancer. However, little is known about the physiological …

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WebApr 1, 2024 · We aimed to investigate the interactive roles of TTC9A and estradiol modulation on behavioral neuroplasticity. The tail suspension immobility data and brain … WebDC Field Value Language; dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Sun, Yang: en: dc.contributor.author: Lufkin, Thomas: en: dc.contributor ...

WebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and estradiol activity is negatively regulated by TTC9A, we hypothesized that the behavioral changes induced by Ttc9a-/- is also mediated by neuroplasticity-related mechanisms. WebFeb 27, 2015 · Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The …

WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts …

WebApr 1, 2024 · Since Ttc9a is induced by estrogen in estrogen target tissues, these results suggest that Ttc9a is a negative regulator of estrogen function through a negative …

WebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity-related gene expression study of brain samples collected in a previous study involving ovariectomized (OVX) Ttc9a-/- mice with estradiol or vehicle treatment. incident in bathgate yesterdayWebAbstract. Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The … inconsistency\u0027s 3lWebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity … inconsistency\u0027s 3fWebPrimePCR™ Template for Probe Assay: TTC9, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. inconsistency\u0027s 3jWebDC Field Value Language; dc.contributor.author: Lim, Lee Wei: en: dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Or, Yu Zuan: en: dc.contributor ... inconsistency\u0027s 3iWebstudies in TTC9A knockout (TTC9A−/−) mice have indicated that TTC9A negatively regulates the action of estrogen. In this study we investigated the role of TTC9A on … inconsistency\u0027s 3kWebEmerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neuroplasticity changes are both implicated in mood regulation, and … inconsistency\u0027s 3q